A review of methods used to extrapolate RCT outcomes using Real World Data and Guidance relating to the matching of data from RCTs and Observational or Registry data banks

This deliverable will review methods used to extrapolate health benefits and treatment costs and will provide guidance on the matching of data from RCTs and Observational or registry data banks It will also outline the manner in which such matched data can form the basis for estimation of longterm outcomes such as average life expectancy