Identified and included 40 patients in SYN-ALD

1 Patients identified with current or prior alcohol overuse and alcoholic liver fibrosis based on the current available stateoftheart noninvasive biomarkers Inclusion criteria also includes a dysbiotic microbiome as defined by WP4 Eligible patients are recruited from alcohol abuse centres outpatient liver clinics emergency rooms and family physicians in Region of Southern Denmark and via national web adverts2 Eighty patients included Collect informed consent After consent patients will be randomised in a 11 doubleblind manner Randomisation stratifies according to drinking status and degree of fibrosis After randomisation all investigations will be performed as described in 12 except liver biopsy