IMI2-PainCare-BioPain-RCT2 protocol: a randomized, double-blind, placebo-controlled, crossover, multicenter trial in healthy subjects to investigate the efects of lacosamide, pregabalin, and tapentadol on biomarkers of pain processing observed by non-invasive neurophysiological measurements of human spinal cord and brainstem activity

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Authors: Leone, Caterina Maria; Di Stefano, Giulia; Di Pietro, Giuseppe; Bloms-Funke, Petra; Boesls, Irmgrad; Caspani, Ombretta; Chapman, Sonya C; Finnerup, Nanna Brix; Garcia-Larrea, Luis; Li, Tom; Goetz, Marcus; Mouraux, André; Pelz, Bernhard; Pogatzki-Zahn,Esther; Schilder, Andreas; Schnetter, Erik; Schubart, Karin; Tracey, Irene; Troconiz, Inaki F; Van Niel, Hans; Vela Hernandez, Josè Miguel; Vincent

Journal title: Trials

Journal number: 3

Journal publisher: BioMed Central

Published year: 2022

DOI identifier: 10.1186/s13063-022-06431-5

ISSN: 1745-6215