mRNAs encoding IL-12 and a decoy-resistant variant of IL-18 synergize to engineer T cells for efficacious intratumoral adoptive immunotherapy

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Authors: Irene Olivera 1 , Elixabet Bolaños 1 , Jose Gonzalez-Gomariz 1 , Sandra Hervas-Stubbs 1 , Karina V Mariño 2 , Carlos Luri-Rey 1 , Iñaki Etxeberria 1 , Assunta Cirella 1 , Josune Egea 1 , Javier Glez-Vaz 1 , Saray Garasa 3 , Maite Alvarez 3 , Iñaki Eguren-Santamaria 1 , Sonia Guedan 4 , Miguel F Sanmamed 3 , Pedro Berraondo 3 , Gabriel A Rabinovich 5 , Alvaro Teijeira 1 , Igna

Journal title: Cell Reports Medicine

Journal publisher: ELSEVIER

Published year: 2023

DOI identifier: 10.1016/j.xcrm.2023.100978

ISSN: 2666-3791