Periodic Reporting for period 1 - Syst-Onco-Herpes (Systemic delivery of oncolytic herpes simplex viruses retargeted to cancer-specific receptors. Virus optimization and business planning.)

Solid tumors that cannot be resected, are metastatic at diagnosis, or progress to metastatic during treatment, are unmet clinical needs and second cause of deaths worldwide (2018). Oncolytic viruses (OVs) are a novel class of replication-competent anti-cancer agents (Lichty...