Discovery of a novel 1,3,4-oxadiazol-2-one-based NLRP3 inhibitor as a pharmacological agent to mitigate cardiac and metabolic complications in an experimental model of diet-induced metaflammation

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Authors: Simone Gastaldi, Carmine Rocca, Eleonora Gianquinto, Maria Concetta Granieri, Valentina Boscaro, Federica Blua, Barbara Rolando, Elisabetta Marini, Margherita Gallicchio, Anna De Bartolo, Naomi Romeo, Rosa Mazza, Francesco Fedele, Pasquale Pagliaro, Claudia Penna, Francesca Spyrakis, Massimo Bertinaria, Tommaso Angelone

Journal title: European Journal of Medicinal Chemistry, Vol. 257

Journal publisher: Elsevier BV

Published year: 2023

DOI identifier: 10.1016/j.ejmech.2023.115542

ISSN: 0223-5234