Lipid vesicles: physical samples; synthesis protocols; characterization database

This task will be focused on the construction of vesicles having different sizes and compositions in a controlled manner (see a-c in figure to the left). Vesicles will incorporate a DNA probe which can hybridize to a specific region of the target DNA. Assembly protocols will be based upon the broad knowledge accumulated in P2’ laboratory in over 15 years of membrane studies. Research efforts will focus on the assembly of lipid vesicles (liposomes) using standard vesicle preparation (dispersion, extrusion, hydration) and characterization (spectroscopic, microscopic, and thermodynamic) techniques, all available at P2’s lab.