D 2.7.1 SP2 Human Brain Organisation - Results for SGA1 Period 1

WPs involved: WP2.1, WP2.2., WP2.3, WP2.4, WP2.5, WP2.6 & WP2.7 Summary of SP Results for M1-12, broken down by Task: • Actual vs. planned results (due & done/due & not done) • Results passed to another Task, WP or SP (due & done/due & not done) • CDP products (due & done/due & not done) • Milestones due and achieved, how validated, by whom. • Milestones due but not achieved, why, impact, corrective action • Publications • SP Roadmap for SGA2, validated by other SPs receiving inputs from your SP NOTE: In order to report fully on the above topics, the Deliverable may need to include information that we would not wish to make public. This material will be included in the Deliverable for the EC and Reviewers, but not in the version published on the HBP public website. COULD INCLUDE: Research results, tools and methods and contribution to initiate the platforms (for Period 1): Description of the data, tools and methods produced and developed in SP2 during the SGA1 phase and their contribution to the platforms. This package will include genetic factors contributing to at least one morphological / cognitive factor, genetic variants and individual genomic profiles, new cytoarchitectonic probabilistic maps of 5 or more human brain regions, mean densities of 15 different receptors in human anterior, mid- and posterior cingulate cortex, early extrastriate and higher visual areas, receptor distributions for selected areas of an initial native Big Brain parcellation, mapped U-fibre bundles and their microstructure, electrophysiological profiles and matching morphologies, massive mapping data from the 12 subjects of the IBC cohort, image-based meta-analysis of multiple functional datasets handled by HBP, framework for multi-modal mapping for one initial region of interest, systematic multi-modal mapping and characterization for at least 3 ROIs, differential laminar‐specific fMRI signals along feedforward ‐and feedback pathways in monkey and humans, model of spatial and feature-based attention effects at the level of cortical columns and layers, excitatory and inhibitory synaptic connections in rodent neocortex and their neuromodulation, effect of ventral midbrain stimulation on cortical representations in monkey, sulcus‐based alignment of cytoarchitectonic and diffusion‐based parcellations, connectivity matrix of the cytoarchitectonic and diffusion‐based parcellations, EEG recording of the first 30 patients localized relative to the HBP connectome nodes, initial prototype of shape model and inter-individual spatial alignment, automatic extraction and identification of sulci from MRI, matching between small and large FoV PLI, HBP workflow for computing cell counts in high-resolution microscopic data.