Periodic Reporting for period 3 - Host-TB (Using CRISPR genome screens and dual transcriptome analyses to dissect host-pathogen interactions in tuberculosis)

With more than 10 million cases annually, tuberculosis (TB) remains a global health problem. TB epidemic is exacerbated by the spread of multidrug-resistant TB. Host-directed therapies can improve immune mechanisms by augmenting the ability of host cells to kill M...