Periodic Reporting for period 1 - SQUALAC (Preclinical development of squalenic acid and gemcitabine squalene nanomedicine)

We have discovered that the linkage of squalene (a natural lipid) to drugs, confers to the resulting bioconjugates the remarkable property to self-assemble as nanoparticles, due to the folded molecular conformation of squalene. This approach is unique and has never been used...