Periodic Reporting for period 1 - FLDcure (A potent Micro-RNA therapeutic for nonalcoholic fatty liver disease (NAFLD))

Summary
MicroRNA (miRNA) family members enable simultaneous modulation of numerous target mRNAs and thereby control entire physiological pathways. We have discovered that engineered overexpression of miR-132 in body tissues triggers rapid and massive accumulation of fat in the liver...