Periodic Reporting for period 4 - Totipotency (Transcriptional and Epigenetic Regulation of Totipotency in Mouse Early Embryos.)

In mammals, fusion of two highly differentiated gametes gives rise to a totipotent zygote capable of developing into a whole organism. It coincides with translation and degradation of maternally provided transcripts, initiation of global transcription called zygotic genome...