Periodic Reporting for period 4 - EpiRIME (Epigenetic Reprogramming, Inheritance and Memory: Dissect epigenetic transitions at fertilisation and early embryogenesis)

Fertilisation and early embryogenesis are the foundations of life. Despite significant progress in developmental biology, several crucial questions remain unanswered:1. How are terminally differentiated gametes reprogrammed to totipotency?2. What is the content and extent of...