Periodic Reporting for period 2 - EpiRIME (Epigenetic Reprogramming, Inheritance and Memory: Dissect epigenetic transitions at fertilisation and early embryogenesis)

Fertilisation and early embryogenesis are the foundations of life. Despite much progress in developmental biology, it remains unclear i) how terminally differentiated gametes are reprogrammed to totipotency ii) what is the content and extent of epigenetic information carried...