Chronic lymphocytic leukemia cells impair mitochondrial fitness in CD8+ T cells and impede CAR T-cell efficacy

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Authors: Jaco A C van Bruggen 1 2 3, Anne W J Martens 1 2 3, Joseph A Fraietta 4 5 6 7, Tom Hofland 1 2 3, Sanne H Tonino 1 2, Eric Eldering 3, Mark-David Levin 8, Peter J Siska 9, Sanne Endstra 1 2 3, Jeffrey C Rathmell 10, Carl H June 4 6, David L Porter 4, J Joseph Melenhorst 4 6, Arnon P Kater 1 2, Gerritje J W van der Windt 1 2 3

Journal title: Blood

Journal publisher: American Society of Hematology

Published year: 2019

Published pages: 44-58

DOI identifier: 10.1182/blood.2018885863

ISSN: 0006-4971