Functional diversification of hybridoma-produced antibodies by CRISPR/HDR genomic engineering

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Authors: Johan M. S. van der Schoot, Felix L. Fennemann, Michael Valente, Yusuf Dolen, Iris M. Hagemans, Anouk M. D. Becker, Camille M. Le Gall, Duco van Dalen, Alper Cevirgel, Jaco A. C. van Bruggen, Melanie Engelfriet, Tomislav Caval, Arthur E. H. Bentlage, Marieke F. Fransen, Maaike Nederend, Jeanette H. W. Leusen, Albert J. R. Heck, Gestur Vidarsson, Carl G. Figdor, Martijn Verdoes, Ferenc A. Scheeren

Journal title: Science Advances

Journal number: 5/8

Journal publisher: Custom publishers

Published year: 2019

Published pages: eaaw1822

DOI identifier: 10.1126/sciadv.aaw1822

ISSN: 2375-2548