Identification of SARS-CoV2-mediated suppression of NRF2 signaling reveals a potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate

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Authors: Antonio Alcami; Julia B. Cadanet; Jinrong Huang; Søren R. Paludan; John Hiscott; Siddharth Balachandran; Marie B. Iversen; Michelle M. Thomsen; Bruno Hernáez; Jan Rehwinkel; Alice Knudsen; Martin R. Jakobsen; Rasmus Ottosen; Trine H. Mogensen; Alon Schneider Hait; Anne L. Thielke; Ensieh Farahani; Esben B. Svenningsen; Manja Idorn; Suraj Peri; Demi van der Horst; Angela Herengt; Yonglu Luo; Vict

Journal title: Nature Communications

Journal number: 3

Journal publisher: Nature Publishing Group

Published year: 2020

DOI identifier: 10.21203/rs.3.rs-31855/v1

ISSN: 2041-1723