Periodic Reporting for period 1 - Cryo-SECOM (Unlocking the potential of cryo-electron tomography by simplification of the sample preparation workflow)

Cryo-electron tomography (cryo-ET) is a powerful technique that can image the native cellular environment at nanometer resolution. The main problem in the current cryo-ET workflow is the multiple critical steps (at least 22) needed to make the sample suitable for analysis...