Periodic Reporting for period 1 - TARGETSET (Commercial feasibility of targeting the histone methyltransferase SETD8 in cancer: New chemical entities and biomarkers.)

This project was focused on the preclinical development of a new class of anticancer medicines, based on the inhibition of a protein named SETD8. This protein had been found to be altered in several tumors, and previous data suggested that molecules that could inhibit its...