Base-editing-mediated dissection of a γ-globin cis-regulatory element for the therapeutic reactivation of fetal hemoglobin expression

Summary

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Authors: Antoniou P, Hardouin G, Martinucci P, Frati G, Felix T, Chalumeau A, Fontana L, Martin J, Masson C, Brusson M, Maule G, Rosello M, Giovannangeli C, Abramowski V, de Villartay JP, Concordet JP, Del Bene F, El Nemer W, Amendola M, Cavazzana M, Cereseto A, Romano O, Miccio A.

Journal title: Nat Commun.

Journal number: continous

Journal publisher: Nature Publishing Group

Published year: 2022

DOI identifier: 10.1038/s41467-022-34493-1

ISSN: 2041-1723