Periodic Reporting for period 4 - MODulATE (Gut microbiota-dependent tryptophan metabolism: role in disease pathogenesis and therapeutic target)

Tryptophan (Trp) is an essential amino acid required for protein biosynthesis and is also a biochemical precursor of metabolites which have major effects on human physiology. In the gastrointestinal tract, Trp metabolism can follow three major pathways, all of which are under...