Gain-of-function DNMT3A mutations cause microcephalic dwarfism and hypermethylation of Polycomb-regulated regions

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Authors: Patricia Heyn, Clare V. Logan, Adeline Fluteau, Rachel C. Challis, Tatsiana Auchynnikava, Carol-Anne Martin, Joseph A. Marsh, Francesca Taglini, Fiona Kilanowski, David A. Parry, Valerie Cormier-Daire, Chin-To Fong, Kate Gibson, Vivian Hwa, Lourdes Ibáñez, Stephen P. Robertson, Giorgia Sebastiani, Juri Rappsilber, Robin C. Allshire, Martin A. M. Reijns, Andrew Dauber, Duncan Sproul, Andrew P. Ja

Journal title: Nature Genetics

Journal number: 51/1

Journal publisher: Nature Publishing Group

Published year: 2019

Published pages: 96-105

DOI identifier: 10.1038/s41588-018-0274-x

ISSN: 1061-4036