Periodic Reporting for period 3 - BARCODED-CELLTRACING (Endogenous barcoding for in vivo fate mapping of lineage development in the blood and immune system)

Summary
The formation of blood and immune cells from bone marrow stem cells ('hematopoiesis') has traditionally been studied by transplantation of stem cells into 'conditioned' recipients whose own immune system had been ablated by irradiation. Such reconstitution provided valuable...
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