Periodic Reporting for period 3 - MITOMAD (Functional characterisation of mitochondrial metabolic adaptations to innate sensing in dendritic cell subsets)

We are investigating how tissue damage and microbial signals lead to mitochondrial reprogramming in dendritic cells (DCs) and macrophages, and how manipulation of mitochondrial metabolism regulates myeloid cell function. This project aims to identify new targets to exploit DCs...