TP53-dependent toxicity of CRISPR/Cas9 cuts is differential across genomic loci and can confound genetic screening

Summary

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Authors: Miguel Alvarez, Josep Biayna, Fran Supek

Journal title: Nature Communications

Journal number: 20411723

Journal publisher: Nature Publishing Group

Published year: 2022

Published pages: 4520

DOI identifier: 10.1038/s41467-022-32285-1

ISSN: 2041-1723