Inverting Small Molecule–Protein Recognition by the Fluorine Gauche Effect: Selectivity Regulated by Multiple H→F Bioisosterism

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Authors: Patrick Bentler, Klaus Bergander, Constantin G. Daniliuc, Christian Mück‐Lichtenfeld, Ravindra P. Jumde, Anna K. H. Hirsch, Ryan Gilmour

Journal title: Angewandte Chemie International Edition

Journal number: 58/32

Journal publisher: John Wiley & Sons Ltd.

Published year: 2019

Published pages: 10990-10994

DOI identifier: 10.1002/anie.201905452

ISSN: 1433-7851