Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages.

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Authors: Runtsch MC, Angiari S, Hooftman A, Wadhwa R, Zhang Y, Zheng Y, Spina JS, Ruzek MC, Argiriadi MA, McGettrick AF, Mendez RS, Zotta A, Peace CG, Walsh A, Chirillo R, Hams E, Fallon PG, Jayamaran R, Dua K, Brown AC, Kim RY, Horvat JC, Hansbro PM, Wang C, O'Neill LAJ.

Journal title: Cell Metabolism

Journal publisher: Cell Press

Published year: 2022

Published pages: 487-501

DOI identifier: 10.1016/j.cmet.2022.02.002

ISSN: 1550-4131