The morphogen Sonic hedgehog inhibits its receptor Patched by a pincer grasp mechanism

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Authors: Amalie F. Rudolf, Maia Kinnebrew, Christiane Kowatsch, T. Bertie Ansell, Kamel El Omari, Benjamin Bishop, Els Pardon, Rebekka A. Schwab, Tomas Malinauskas, Mingxing Qian, Ramona Duman, Douglas F. Covey, Jan Steyaert, Armin Wagner, Mark S. P. Sansom, Rajat Rohatgi, Christian Siebold

Journal title: Nature Chemical Biology

Journal number: 15/10

Journal publisher: Nature Publishing Group

Published year: 2019

Published pages: 975-982

DOI identifier: 10.1038/s41589-019-0370-y

ISSN: 1552-4450