Rapid Discovery and Structure–Activity Relationships of Pyrazolopyrimidines That Potently Suppress Breast Cancer Cell Growth via SRC Kinase Inhibition with Exceptional Selectivity over ABL Kinase

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Authors: Craig Fraser, John C. Dawson, Reece Dowling, Douglas R. Houston, Jason T. Weiss, Alison F. Munro, Morwenna Muir, Lea Harrington, Scott P. Webster, Margaret C. Frame, Valerie G. Brunton, E. Elizabeth Patton, Neil O. Carragher, Asier Unciti-Broceta

Journal title: Journal of Medicinal Chemistry

Journal number: 59/10

Journal publisher: American Chemical Society

Published year: 2016

Published pages: 4697-4710

DOI identifier: 10.1021/acs.jmedchem.6b00065

ISSN: 0022-2623