Periodic Reporting for period 3 - TotipotentZygotChrom (Mechanisms of chromatin organization and reprogramming in totipotent mammalian zygotes)

Our research addresses the question of how life starts. Fertilization of egg by sperm generates a one-cell embryo that has the potential to generate an entire organism. Initially, the one-cell embryo is not competent to express its genome. Instead, this large cell is...