Astrocyte-targeted gene delivery of interleukin 2 specifically increases brain-resident regulatory T cell numbers and protects against pathological neuroinflammation

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Authors: "Lidia Yshii # 1 2 3, Emanuela Pasciuto # 1 2 3, Pascal Bielefeld # 4 5, Loriana Mascali 1 2, Pierre Lemaitre 1 2, Marika Marino 1 3, James Dooley 5, Lubna Kouser 5, Stijn Verschoren 1 3, Vasiliki Lagou 1 2, Hannelore Kemps 6, Pascal Gervois 6, Antina de Boer 1 3, Oliver T Burton 5, Jérôme Wahis 1 3, Jens Verhaert 1 3, Samar H K Tareen 5, Carlos P Roca 5, Kailash Singh 5, Carly E Whyte 5, Axelle"

Journal title: Nature Immunology

Journal number: Online ahead of print

Journal publisher: Nature Publishing Group

Published year: 2022

DOI identifier: 10.1038/s41590-022-01208-z

ISSN: 1529-2908