Age-of-diagnosis dependent ileal immune intensification and reduced alpha-defensin in older versus younger pediatric Crohn Disease patients despite already established dysbiosis

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Authors: Yael Haberman, Melanie Schirmer, Phillip J. Dexheimer, Rebekah Karns, Tzipi Braun, Mi-Ok Kim, Thomas D. Walters, Robert N. Baldassano, Joshua D. Noe, Joel Rosh, James Markowitz, Wallace V. Crandall, David R. Mack, Anne M. Griffiths, Melvin B. Heyman, Susan S. Baker, Richard Kellermayer, Dedrick Moulton, Ashish S. Patel, Ajay S. Gulati, Steven J. Steiner, Neal LeLeiko, Anthony Otley, Maria Oliva-He

Journal title: Mucosal Immunology

Journal number: 12/2

Journal publisher: Nature Publishing Group

Published year: 2019

Published pages: 491-502

DOI identifier: 10.1038/s41385-018-0114-4

ISSN: 1933-0219