Targeting purine synthesis in ASS1-expressing tumors enhances the response to immune checkpoint inhibitors

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Authors: Rom Keshet, Joo Sang Lee, Lital Adler, Muhammed Iraqi, Yarden Ariav, Lisha Qiu Jin Lim, Shaul Lerner, Shiran Rabinovich, Roni Oren, Rotem Katzir, Hila Weiss Tishler, Noa Stettner, Omer Goldman, Hadas Landesman, Sivan Galai, Yael Kuperman, Yuri Kuznetsov, Alexander Brandis, Tevi Mehlman, Sergey Malitsky, Maxim Itkin, S. Eleonore Koehler, Yongmei Zhao, Keyur Talsania, Tsai-wei Shen, Nir Peled, Igor

Journal title: Nature Cancer

Journal number: 1/9

Journal publisher: Nature Cancer

Published year: 2020

Published pages: 894-908

DOI identifier: 10.1038/s43018-020-0106-7

ISSN: 2662-1347