Allele-Specific Silencing of Mutant mRNA Rescues Ultrastructural and Arrhythmic Phenotype in Mice Carriers of the R4496C Mutation in the Ryanodine Receptor Gene ( RYR2 )Novelty and Significance

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Authors: Rossana Bongianino, Marco Denegri, Andrea Mazzanti, Francesco Lodola, Alessandra Vollero, Simona Boncompagni, Silvia Fasciano, Giulia Rizzo, Damiano Mangione, Serena Barbaro, Alessia Di Fonso, Carlo Napolitano, Alberto Auricchio, Feliciano Protasi, Silvia G. Priori

Journal title: Circulation Research

Journal number: 121/5

Journal publisher: Lippincott Williams & Wilkins Ltd.

Published year: 2017

Published pages: 525-536

DOI identifier: 10.1161/CIRCRESAHA.117.310882

ISSN: 0009-7330