A single-amino acid substitution in the adaptor LAT accelerates TCR proofreading kinetics and alters T-cell selection, maintenance and function

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Authors: Wan-Lin Lo, Miriam Kuhlmann, Gabrielle Rizzuto, H. Atakan Ekiz, Elizabeth M. Kolawole, Monica P. Revelo, Rakieb Andargachew, Zhongmei Li, Yuan-Li Tsai, Alexander Marson, Brian D. Evavold, Dietmar Zehn & Arthur Weiss

Journal title: Nature Immunology

Journal number: 2023 Apr;24(4):676-689

Journal publisher: Nature Publishing Group

Published year: 2023

Published pages: 676-689

DOI identifier: 10.1038/s41590-023-01444-x

ISSN: 1529-2908