Periodic Reporting for period 4 - AUROMYC (N-Myc and Aurora A: From Protein Stability to Chromosome TopologyN-Myc and Aurora A: From Protein Stability to Chromosome TopologyMyc and Aurora A: From Protein Stability to Chromosome Topology)

The question that was addressed in this project was to understand the function of a complex of the MYCN protein with the Aurora-A kinase. The MYCN protein is an oncoprotein that drives the development of many, mainly neuroendocrine tumours. For example, many pediatric cancers...