Evolutionary repurposing of a sulfatase: A new Michaelis complex leads to efficient transition state charge offset

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Authors: Charlotte M. Miton, Stefanie Jonas, Gerhard Fischer, Fernanda Duarte, Mark F. Mohamed, Bert van Loo, Bálint Kintses, Shina C. L. Kamerlin, Nobuhiko Tokuriki, Marko Hyvönen, Florian Hollfelder

Journal title: Proceedings of the National Academy of Sciences

Journal number: 115/31

Journal publisher: National Academy of Sciences

Published year: 2018

Published pages: E7293-E7302

DOI identifier: 10.1073/pnas.1607817115

ISSN: 0027-8424