Balancing Specificity and Promiscuity in Enzyme Evolution: Multidimensional Activity Transitions in the Alkaline Phosphatase Superfamily

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Authors: Bert van Loo, Christopher D. Bayer, Gerhard Fischer, Stefanie Jonas, Eugene Valkov, Mark F. Mohamed, Anastassia Vorobieva, Celine Dutruel, Marko Hyvönen, Florian Hollfelder

Journal title: Journal of the American Chemical Society

Journal number: 141/1

Journal publisher: American Chemical Society

Published year: 2018

Published pages: 370-387

DOI identifier: 10.1021/jacs.8b10290

ISSN: 0002-7863