Periodic Reporting for period 4 - StemNicheOnWaveCrest (New therapies for myeloproliferative diseases based on multi-stage and -system analyses of the haematopoietic stem-cell niche)

Until recently, it was believed that cancer was only driven by changes inside cells: genes become mutated, cells grow uncontrolled, and a tumour arises. However, recent evidence indicates that the surrounding environment where tumour cells live also plays an important role in...