MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition

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Authors: Lieselotte Vande Walle, Irma B. Stowe, Pavel Šácha, Bettina L. Lee, Dieter Demon, Amelie Fossoul, Filip Van Hauwermeiren, Pedro H. V. Saavedra, Petr Šimon, Vladimír Šubrt, Libor Kostka, Craig E. Stivala, Victoria C. Pham, Steven T. Staben, Sayumi Yamazoe, Jan Konvalinka, Nobuhiko Kayagaki, Mohamed Lamkanfi

Journal title: PLOS Biology

Journal number: 17/9

Journal publisher: PLOS

Published year: 2019

Published pages: e3000354

DOI identifier: 10.1371/journal.pbio.3000354

ISSN: 1545-7885