Periodic Reporting for period 3 - CAN-IT-BARRIERS (Disruption of systemic and microenvironmental barriers to immunotherapy of antigenic tumors)

To fully comprehend the mechanisms of intra-tumoral and systemic immune barriers that limit the efficacy of ground-breaking immunotherapies, we use immunocompetent genetically engineered mouse cancer models of cancer (GEMM), enabling the investigation of susceptibility and...