Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD

Summary

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Authors: Graeme Hewitt, Valerie Borel, Sandra Segura-Bayona, Tohru Takaki, Phil Ruis, Roberto Bellelli, Laura C. Lehmann, Lucia Sommerova, Aleksandra Vancevska, Antonia Tomas-Loba, Kang Zhu, Christopher Cooper, Kasper Fugger, Harshil Patel, Robert Goldstone, Deborah Schneider-Luftman, Ellie Herbert, Gordon Stamp, Rachel Brough, Stephen Pettitt, Christopher J. Lord, Stephen C. West, Ivan Ahel, Dragana Ahel,

Journal title: Molecular Cell

Journal number: 81/4

Journal publisher: Cell Press

Published year: 2021

Published pages: 767-783.e11

DOI identifier: 10.1016/j.molcel.2020.12.006

ISSN: 1097-2765