Periodic Reporting for period 4 - NterAct (Discovery and functional significance of post-translational N-terminal acetylation)

In mammalian cells, around 80% of cellular proteins are subjected to N-terminal (Nt) acetylation, thus making this one of the most abundant protein modifications. For most Nt-acetylated proteins the acetyl group is added co-translationally by the action of ribosome-associated...