ALS-linked PFN1 variants exhibit loss and gain of functions in the context of formin-induced actin polymerization

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Authors: Eric J. Schmidt, Salome Funes, Jeanne E. McKeon, Brittany R. Morgan, Sivakumar Boopathy, Lauren C. O’Connor, Osman Bilsel, Francesca Massi, Antoine Jégou, Daryl A. Bosco

Journal title: Proceedings of the National Academy of Sciences

Journal number: 118/23

Journal publisher: National Academy of Sciences

Published year: 2021

Published pages: e2024605118

DOI identifier: 10.1073/pnas.2024605118

ISSN: 0027-8424