Periodic Reporting for period 4 - DIvA (Chromatin function in DNA Double Strand breaks repair: Prime, repair and restore DSB Inducible via AsiSI)

Maintaining genome integrity is of crucial importance for multicellular organisms. This is illustrated by the variety of human diseases, associated with DNA repair defects. Among the lesions that can occur on the genome, DNA Double Strand break (DSB) are the most deleterious...