Periodic Reporting for period 4 - INFLAME (Deciphering the host and microbial grounds that license inflammasome-mediated execution)

Inflammasomes are intracellular multi-protein complexes that play essential functions in immunity against microbial pathogens. Upon microbial sensing, inflammasomes induce protease caspase-1-dependent maturation and release of the pro-inflammatory cytokines interleukin...