Periodic Reporting for period 1 - I.am.a.LAD (From chromatin fibers to lamina-associated domains: what are the recognition determinants?)

About 2 meters of genomic DNA are confined in a 10 µm cell nucleus. Genome folding needs to be controlled at multiple levels to achieve such a level of compaction. One such mechanism involves contacts of the genome with the nuclear lamina (NL), a proteinaceous meshwork that...