3-Fluoro-4-hydroxyprolines: Synthesis, Conformational Analysis, and Stereoselective Recognition by the VHL E3 Ubiquitin Ligase for Targeted Protein Degradation

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Authors: Andrea Testa, Xavier Lucas, Guilherme V. Castro, Kwok-Ho Chan, Jane E. Wright, Andrew C. Runcie, Morgan S. Gadd, William T. A. Harrison, Eun-Jung Ko, Daniel Fletcher, Alessio Ciulli

Journal title: Journal of the American Chemical Society

Journal number: 140/29

Journal publisher: American Chemical Society

Published year: 2018

Published pages: 9299-9313

DOI identifier: 10.1021/jacs.8b05807

ISSN: 0002-7863