Periodic Reporting for period 1 - VWF and NETs (Investigating the interplay between VWF, platelets, and neutrophil extracellular traps inpathologies involving thrombosis of the microvasculature)

Thrombosis is a complex process involving activation of endothelial cells, and their release of Weibel-Palade body contents such as von Willebrand factor (VWF) and P-selectin. This in turn recruits platelets which form aggregates, and leukocytes such as neutrophils. The recent...