Periodic Reporting for period 1 - Rotaxane-DNA (Rotaxane-Oligonucleotides: Stimuli-Responsive Mechanically Interlocked Architectures to Control Oligonucleotide Activity and Gene Transcription)

During this MSCA, I helped develop a new type of synthetic but biocompatible DNA. The key innovative feature of my work was that the DNA molecule was wrapped in a circular molecule to create a structure called a rotaxanes. The key challenge I addressed in my project was how to...