Periodic Reporting for period 1 - ENVERESP (Crosstalk between nuclear envelope and DNA Damage Response: Role of nucleoporin TPR in the maintenance of genomic integrity)

Each cell in the human body receives thousands of DNA lesions per day. To counteract risks posed by DNA damage, cells have evolved a signaling network called the DNA-damage response (DDR). This mechanism allows cells to sense DNA lesions, signal their presence and promote...